DHT Hair Loss

DHT Molecular StructureDHT Molecular Structure

DHT hair loss is the leading cause of losing hair in men and women alike. It affects more men than women because men have higher levels of Testosterone, and DHT comes from that hormone.

What does DHT stand for?

When you first saw the word DHT you probably wondered what it meant. You will see something that it is not, although it seems like a Lego® toy if you look above. It is instead the molecular structure of DHT.

Indeed, I'm not here to give you a science class or talk about toys. I'm here to help you understand what DHT means and how it can have DHT hair loss.

DHT means dihydrotestosterone, which is one of the causes of hair loss.

If you split the word, it would say: di-hydro-testo-sterone; di means two; hydro means hydrogen. So di-hydro shows that there are two hydrogen molecules. I know it sounds like a science class.

So the word testo comes from testis, which means testicles, or the male organ that produces sperm. What do we have left? Yes, sure, sterone, which means it is a steroid hormone.

But what is DHT hair loss? Can you counter it? To answer those questions, we have to know what testosterone is.

What is Testosterone

Testosterone is the steroid hormone that controls the development and maintenance of a man's sexual organs, sexual desire, sperm production, muscle development, deep voice, and body hair.

It is in both humans and animals. In the case of men, the production of this hormone is in the testicles and the prostate.

In women, it forms in the ovaries, although in smaller amounts. Testosterone begins to accumulate at puberty, and varies in quantity, starting at age 30.

Men have a concentration ten times higher than women. However, the latter is more sensitive to the change from the hormone to DHT.

The maximum level of testosterone in a man is 1000 ng/dl, according to Men's Health. That is 1000 nanograms per deciliter. Now don't ask me what the meaning of that is. The only thing I can tell you is that it is a measure known to doctors and laboratories.

I once asked my urologist, what happens if someone reaches the maximum amount, and he said the testicles begin to atrophy. So it doesn't seem like a good idea to go that far.

Well, you know what testosterone is. Now you have to know what DHT is and its effects on hair follicles. First, let's see what it is.

What is DHT Hair Loss?

Well, you know what testosterone is. Now you have to understand what DHT hair loss is and what the effects are on hair follicles. First, let's see what it is.

DHT is a by-product of testosterone. The conversion of testosterone to DHT is about 10 percent. A derivative is a product obtained from a principal, or it can also be an unexpected consequence.

DHT meets both of these definitions well, first., it is a by-product of testosterone, and second, it also produces an unexpected consequence.

Now it all boils down to one question, what do testosterone levels have to do with hair loss, and why does DHT have an unexpected consequence?

Does Testosterone cause Hair Loss?

Some people think that testosterone levels in bald men should skyrocket. But that's how it is? Will these men be more prone to dht hair loss?

According to different studies, there is proof that there is no difference in hair loss between the person who has a high level of testosterone and the one who does not.

The difference is how the hair follicles respond to hormones or hormonal changes. Men who go bald when they are still young have hair follicles that are more sensitive to testosterone.

Dihydrotestosterone works in synthesis mode. It means that two or more elements come together to make something new, either in the testicles, the prostate, the hair follicles, and the two adrenal glands, which are the glands above the kidneys. 

Ten percent of the testosterone binds to the enzyme 5-a reductase and the two hydrogen molecules to form dht.

To understand this better, imagine that you want to make a cake. You have milk, eggs, flour, sugar, and vanilla. What happens when you mix those ingredients? You would have a mix of those ingredients, but you still don't have a cake.

What do you need to do it? Heat, yes, fire. If you don't cook the ingredients, they will never become a cake. When cooked, they are modified or transformed into something else, which in this case would be a cake.

So when you mix all these elements and apply heat to them, they transform into a delicious dessert. At least, I hope so.

In the same way, when two hydrogen molecules mix with testosterone and the enzyme 5-a reductase, dht forms. You can say that the enzyme 5-a reductase is the fire that unites these elements.

The only thing is that when dihydrotestosterone forms, it is not always as delicious as a dessert since it converts into dht hair loss. That is why we say that produces an unexpected result.

One of the causes of hair loss is that testosterone converts into dht in the hair follicles.

We still don't know why dht is essential for the growth of body hair but fatal for hair on the head or scalp.

It causes hair follicles to shrink until many of them eventually die. The hair that is still alive shrinks so much that you can hardly see it through a magnifying glass.

Reasons for hair loss include genetics, hormones, and the environment. In the case of dht hair loss, it is classified as a hormonal cause because the hormone testosterone is converted to dht by the enzyme 5-a reductase.

Weightlifters, for instance, use anabolic steroids to increase their testosterone levels. We may not know that it also increases the probability of losing hair because 10 percent of testosterone converts into dht.

It binds to the same places as testosterone but more intensely and for much longer. What are the consequences of this happening on the scalp?

·        atrophy of hair follicles

·        the hair comes out with more difficulty because the follicle membranes harden more and more

·        the hair cannot take advantage of the proteins, vitamins, and minerals that we consume because it has little blood circulation. Therefore, it does not grow strong and healthy

·        the hair becomes thinner

·        the anagen, or hair growth phase, shortens over time

·         the hair loss is more noticeable

·         Finally, the hair does not grow in the affected follicles

Hair growth is a cycle and has four phases: anagen, catagen, telogen, and exogen. When those four stages are complete, it goes back to the anagen phase, where the hair grows.

Male pattern hair loss begins when in the anagen phase, which is where the hair grows, does not grow back the same thickness but is somewhat thinner.

Over time the anagen phase becomes shorter and shorter. The hair comes out with more difficulty until it looks like baby hair. In the end, it doesn't peek out again.

To understand this better, you can read the telogen effluvium article. Soon, I will talk about how to counteract dht.